I had a metermine week sample and it was horrible. I'm day 2 on the original duromine and the only side effect so far has been a restless sleep the first night, last night i slept like a baby so hopefully that's the worst of it. my doctor said most people have less side effects on duromine. perhaps go get the original and see of it changes how your body reacts. its a little more expensive but as they say, you get what you pay for.