I've been told (by doc and health care manager), that in the beginning of using duromine, you will lose weight rapidly then almost always hit a plateau, but not to fear, you will begin to lose the weight again after a lil while (could be a week or two). If youv been using duromine for a while and have lost a fair amount of weight, and then you hit a plateau, this usually calls for a diet change and exercise routine change up. Also you will need to actually eat more (calorie increase), in order to burn more as the body has become accustomed to the new way of things and needs a new shake up to keep the ball rolling. Have a chat with your doc and see what they say. Hopefully iv passed on some helpful, and more importantly, correct, advise to help.